{"id":19059,"date":"2025-03-20T08:25:12","date_gmt":"2025-03-19T23:25:12","guid":{"rendered":"https:\/\/www.sanctionlab.com\/?p=19059"},"modified":"2025-03-20T10:42:17","modified_gmt":"2025-03-20T01:42:17","slug":"cgt-%ed%82%a4%ec%9a%b8-%eb%ac%98%ec%88%98-%ec%8b%9c%ed%96%89-%ed%95%9c%eb%8b%ac-%ec%a0%81%ec%9a%a9-%ec%82%ac%eb%a1%80%eb%8a%94-%ec%95%84%ec%a7%81-%ec%97%86%eb%8b%a4","status":"publish","type":"post","link":"https:\/\/www.sanctionlab.com\/?p=19059","title":{"rendered":"CGT \ud0a4\uc6b8 ‘\ubb18\uc218’ \uc2dc\ud589 \ud55c\ub2ec, \uc801\uc6a9 \uc0ac\ub840\ub294 \uc544\uc9c1 \uc5c6\ub2e4"},"content":{"rendered":"

|\u2460\uc5f0\uad6c \ud658\uc790 \ubc94\uc704 \ud655\ub300, \uce58\ub8cc \uc81c\ub3c4 \ub3c4\uc785\u2026’\uc815\ucc45\uc704\u00b7\uc2ec\uc758\uc704’ \uc5ed\ud560\ub860 \ubd80\uc0c1<\/h3>\n

\uc7ac\uc0dd\uc758\ub8cc \ud65c\uc131\ud654 \uc81c\ub3c4\ub97c \uc120\uc81c\uc801\uc73c\ub85c \ub9cc\ub4e0 \uc77c\ubcf8\uc744 \ud55c\uad6d\uc774 \ub4a4\ucad3\uace0 \uc788\ub2e4. \uc62c\ud574 2\uc6d4\ubd80\ud130 \ucca8\uc0dd\ubc95 \uac1c\uc815\uc548\uc774 \ubcf8\uaca9 \uc2dc\ud589\ub418\uba74\uc11c \uac04\uadf9\uc740 \ub354 \uc881\ud600\uc84c\ub2e4\ub294 \ud3c9\uac00\ub2e4.<\/p>\n

\ub2ec\ub77c\uc9c4 \ucca8\uc0dd\ubc95\uc740 \uad00\ub828 \uc5f0\uad6c \ub300\uc0c1\uc774 \ub420 \ud658\uc790 \ubc94\uc704\ubd80\ud130 \ub300\ud3ed \uc190\ubd24\ub2e4. \uac1c\ubc1c\uc0ac\uac00 \uc120\ud0dd\ud560 \uc218 \uc788\ub294 \uc801\uc751 \uc9c8\ud658\uc758 \ud3ed\uc774 \ub113\uc5b4\uc9c8 \uc218 \uc788\ub2e4\ub294 \uc804\ub9dd\uc774\ub2e4. \ub610 \uc7ac\uc0dd\uc758\ub8cc \uc57d\ubb3c\uc758 \uc0c1\uc5c5\ud654 \uc774\uc804\uc5d0\ub3c4 \uc77c\ubd80 \ube44\uc6a9\uc744 \ud658\uc790\uc5d0\uac8c \ubd80\uacfc\ud560 \uc218 \uc788\ub3c4\ub85d ‘\uce58\ub8cc \uc81c\ub3c4’\ub97c \ub3c4\uc785\ud55c\ub2e4.<\/p>\n

\ucca8\uc0dd\ubc95 \uac1c\uc815\uc548\uc774 \ubcf8\uaca9 \uc2dc\ud589\ub41c \uc9c0 \ud55c\ub2ec\ub9cc\uc5d0 \ubcc0\ud654\ub97c \uccb4\uac10\ud560\ub9cc\ud55c \uc0ac\ub840\ub294 \ub098\uc624\uc9c0 \uc54a\uace0 \uc788\ub2e4. \uadf8\ub7fc\uc5d0\ub3c4 \uc2e0\uc57d\uac1c\ubc1c\uc774\ub098 \uc704\ud0c1\uac1c\ubc1c\uc0dd\uc0b0(CDMO), ‘\uc18c\uc7ac\u00b7\uc7a5\ube44\u00b7\ubd80\ud488’ \ub4f1 \uac01 \ubd80\ubb38\ubcc4 \uc138\ud3ec\uc720\uc804\uc790\uce58\ub8cc\uc81c(CGT) \uae30\uc5c5\ub4e4\uc774 \uc774\ubc88 \uac1c\uc815\uc548\uc5d0 \ud61c\ud0dd\uc744 \ub204\ub9ac\uace0\uc790 \ubc1c\ube60\ub974\uac8c \uc6c0\uc9c1\uc774\uace0 \uc788\ub2e4.<\/p>\n

\u25c7\uc7ac\uc0dd\uc758\ub8cc\u00a0<\/strong>\uc704\ud5d8\ub3c4, \uc548\uc804\uc131 \ub370\uc774\ud130 \uc788\uc73c\uba74 \ubcc0\uacbd \uac00\ub2a5<\/strong><\/p>\n

\ucca8\uc0dd\ubc95\uc740 2020\ub144\uc5d0 \ucc98\uc74c \uc2dc\ud589\ub410\ub2e4. \uc77c\ubcf8\uc758 ‘\uc7ac\uc0dd\uc758\ub8cc \ub4f1\uc758 \uc548\uc804\uc131\uc758 \ud655\ubcf4 \ub4f1\uc5d0 \uad00\ud55c \ubc95\ub960(\uc7ac\uc0dd\uc758\ub8cc\uc548\uc804\ubc95)’\ubcf4\ub2e4 6\ub144 \ub2a6\uc740 \uc2dc\uc810\uc774\uc5c8\ub2e4. \uc7ac\uc0dd\uc758\ub8cc \uc120\uc9c4\uad6d\uc778 \uc77c\ubcf8\uc758 \uc0ac\ub840\ub97c \ucc38\uace0\ud55c \ub9cc\ud07c \ub450 \ubc95\uc740 \ucc98\uc74c\ubd80\ud130 \ub2ee\uc544 \uc788\uc5c8\ub2e4.<\/p>\n

\"\"<\/div>\n

\ud2b9\ud788 \uc7ac\uc0dd\uc758\ub8cc\uc758 \uc815\uc758\uc640 \ubd84\ub958\ud558\ub294 \ubc29\uc2dd\uc740 \uc77c\ubcf8\uacfc \ud55c\uad6d\uc774 \ub300\ub3d9\uc18c\uc774\ud558\ub2e4. \uc77c\ubcf8\uc5d0\uc11c\ub294 \ucca8\ub2e8 \uc7ac\uc0dd\uc758\ub8cc\uc5d0 \ub300\ud574 \uac00\uacf5\ud55c \uc138\ud3ec \ub610\ub294 \uad00\ub828 \uae30\uc220\uc744 \uc774\uc6a9\ud574 \uc2e4\uc2dc\ud558\ub294 \uc758\ub8cc\ud589\uc704\ub77c\uace0 \uc815\uc758\ud55c\ub2e4.<\/p>\n

\ucca8\uc0dd\ubc95 \uac1c\uc815\uc548 \uc81c2\uc870 1\ud56d\uc5d0\uc11c\ub294 \ucca8\ub2e8 \uc7ac\uc0dd\uc758\ub8cc\ub97c \uc0ac\ub78c\uc758 \uc2e0\uccb4 \uad6c\uc870 \ub610\ub294 \uae30\ub2a5 \uc7ac\uc0dd\uc744 \uc704\ud574 \uc778\uccb4\uc138\ud3ec \ub4f1\uc744 \ud65c\uc6a9\ud55c \uce58\ub8cc \uc2dc\ub3c4\ub85c \uc815\uc758\ud55c\ub2e4. \uc5ec\uae30\uc11c \uc778\uccb4\uc138\ud3ec\ub294 \uc778\uccb4\uc5d0\uc11c \uc720\ud574\ub780 \uc904\uae30\uc138\ud3ec\ub098 \uc870\ud608\ubaa8\uc138\ud3ec, \uccb4\uc138\ud3ec, \uba74\uc5ed\uc138\ud3ec, \uc774\uc885\uc138\ud3ec \ub4f1\uc774 \ud3ec\ud568\ub41c\ub2e4.<\/p>\n

\uc591\uad6d \ubaa8\ub450 \ucca8\ub2e8 \uc7ac\uc0dd\uc758\ub8cc\uc758 \uc704\ud5d8\ub3c4\ub97c \uc138 \ub2e8\uacc4\ub85c \ub098\ub204\uace0 \uc788\uc73c\uba70 \uac1c\ubc1c \ub2e8\uacc4\ubcc4 \uc2ec\uc758 \uc808\ucc28\ub97c \uc88c\uc6b0\ud560 \uae30\uc900\uc73c\ub85c \uc791\uc6a9\ud55c\ub2e4. \uc790\uac00(\ubcf8\uc778)\uc138\ud3ec\uc774\uba74\uc11c \ucd5c\uc18c\ub85c \uc870\uc791\ud558\uba74 \uc800\uc704\ud5d8\uc774\uace0 \uc790\uac00\uc138\ud3ec \ub77c\ub3c4 \ubc30\uc591\uc744 \uac70\uce58\uba74 \uc911\uc704\ud5d8\uc774\ub2e4.<\/p>\n

‘\ud0c0\uc778\uc758 \uc138\ud3ec(\ub3d9\uc885\uc138\ud3ec)’\ub294 \ucd5c\uc18c\ub85c \uc870\uc791\ud558\ub354\ub77c\ub3c4 \uc911\uc704\ud5d8\uc73c\ub85c \ubd84\ub958\ub41c\ub2e4. \uc544\ubb34\ub9ac \uc790\uac00\uc138\ud3ec\ub77c\ub3c4 \ubc30\uc544\uc904\uae30\uc138\ud3ec\ub098 \uc720\ub3c4\ub9cc\ub2a5\uc904\uae30\uc138\ud3ec(iPSC) \ub4f1 \ubd84\ud654 \ub2a5\ub825\uc774 \uc788\ub294 \uc138\ud3ec\ub098 \ub3d9\ubb3c\uc5d0\uc11c \uc720\ub798\ud55c \uc774\uc885\uc138\ud3ec\ub294 \ubaa8\ub450 \uace0\uc704\ud5d8\uc774\ub2e4.<\/p>\n

\uadf8\ub7f0\ub370 \ucca8\uc0dd\ubc95 \uac1c\uc815\uc548\uc5d0\uc11c\ub294 \uace0\uc704\ud5d8\uc73c\ub85c \ubd84\ub958\ub41c \ubb3c\uc9c8\ub3c4 \uc694\uac74\uc744 \uac16\ucd94\uba74 \uc911\uc704\ud5d8\uc73c\ub85c \ub0ae\ucd94\ub294 \uac83\ub3c4 \uac00\ub2a5\ud574\uc84c\ub2e4. \uc608\ub97c \ub4e4\uba74 \uc790\uac00\uba74\uc5ed\uc138\ud3ec\ub97c \ubc30\uc591\ud558\uba74 \uc911\uc704\ud5d8\uc774\uc9c0\ub9cc \ub192\uc740 \uc21c\ub3c4 \ub4f1 \uc548\uc804\uc131 \ub370\uc774\ud130\ub97c \uc785\uc99d\ud558\uba74 \uc2ec\uc758\ub97c \uac70\ucc98 \uc800\uc704\ud5d8\uc73c\ub85c \ubd84\ub958\ub420 \uc218 \uc788\ub3c4\ub85d \uaddc\uc81c\ub97c \uc644\ud654\ud588\ub2e4.<\/p>\n

\u25c7\uc77c\ubcf8 \ub530\ub77c \uc7a1\uc740 \ub450 \uac00\uc9c0, ‘\ud658\uc790 \ubc94\uc704’\uc640 ‘\uce58\ub8cc\uc81c\ub3c4’<\/strong><\/p>\n

\uc77c\ubcf8\uc758 \uc7ac\uc0dd\uc758\ub8cc\uc548\uc804\ubc95\uacfc \ud55c\uad6d\uc758 \ucd08\uae30 \ucca8\uc0dd\ubc95\uc5d0\uc11c \uac00\uc7a5 \ucc28\uc774\uac00 \ub098\ub294 \uc810\uc740 \ucca8\ub2e8 \uc7ac\uc0dd\uc758\ub8cc\uc758 \uc5f0\uad6c \ub300\uc0c1\uc774 \ub420 \ud658\uc790 \ubc94\uc704\uc640 \uce58\ub8cc \uc81c\ub3c4\uc758 \uc720\ubb34\uc600\ub2e4. \uc62c\ud574 2\uc6d4 21\uc77c\ubd80\ud130 \uc2dc\ud589\ub41c \ucca8\uc0dd\ubc95 \uac1c\uc815\uc548\uc5d0\uc11c \ub208\uc5ec\uaca8 \ubcfc \uc810\ub3c4 \uc5ec\uae30\uc5d0 \uc788\ub2e4.<\/p>\n

\"\"<\/div>\n

\uc77c\ubcf8\uc740 \ucca8\ub2e8\uc7ac\uc0dd\uc758\ub8cc\uc758 \uc5f0\uad6c \ub300\uc0c1\uc744 ‘\ud658\uc790’\ub85c \uaddc\uc815\ud558\uace0 \uc788\ub2e4. \ub610 \ucca8\ub2f9 \uc7ac\uc0dd\uc758\ub8cc\ub97c \uc5f0\uad6c\uc790 \uc784\uc0c1\uacfc \uce58\ub8cc\ub85c \uad6c\ubd84\ud55c\ub2e4. \ud559\uc220\ubaa9\uc801\uc758 \uc5f0\uad6c\uc790 \uc784\uc0c1\uc5d0 \ucc38\uc5ec\ud55c \ud658\uc790\uc5d0\uac8c \uc57d\ubb3c\uc744 \ud22c\uc57d\ud574\ub3c4 \ube44\uc6a9\uc744 \ubd80\uacfc\ud560 \uc218 \uc5c6\uc9c0\ub9cc, \uce58\ub8cc \ubaa9\uc801\uc73c\ub85c \uc2b9\uc778\ub410\uc744 \uacbd\uc6b0 \ube44\uc6a9\uc744 \ubc1b\uc744 \uc218 \uc788\ub2e4.<\/p>\n

\ucd08\uae30 \ucca8\uc0dd\ubc95\uc5d0\uc11c\ub294 \uc77c\ubcf8\uacfc \ub2e4\ub974\uac8c \ucca8\ub2e8 \uc7ac\uc0dd\uc758\ub8cc\uc758 \uc5f0\uad6c \ub300\uc0c1\uc790\ub97c ‘\uc911\ub300\u00b7\ud76c\uadc0\u00b7\ub09c\uce58’ \uc9c8\ud658\uc790\ub85c \ud55c\uc815\ud588\ub2e4. \ub610 \uc0c1\uc5c5\ud654\ud558\uc9c0 \uc54a\ub294\ub2e4\uba74 \uc5f0\uad6c\uc790 \uc784\uc0c1\uc740 \ubb3c\ub860\uc774\uace0 \uce58\ub8cc \ubaa9\uc801\uc73c\ub85c \ud658\uc790\uc5d0\uac8c \ud22c\uc57d\ub418\ub3c4 \ube44\uc6a9\uc744 \ubd80\uacfc\ud560 \uc218 \uc5c6\uc5c8\ub2e4. \uadf8\ub3d9\uc548 \ub9ce\uc740 \uc138\ud3ec\uce58\ub8cc \uae30\uc5c5\uc774 \uc784\uc0c1\uc758\uc5d0 \uc694\uccad\uc5d0 \ub530\ub77c ‘\uce58\ub8cc \ubaa9\uc801\uc758 \uc0ac\uc6a9 \uc2b9\uc778\uc744 \ud68d\ub4dd\ud588\ub2e4’\ub294 \uc18c\uc2dd\uc744 \uc804\ud55c \uc801\uc774 \uc788\uc9c0\ub9cc \ubaa8\ub4e0 \ud22c\uc57d \ube44\uc6a9\uc744 \uae30\uc5c5\uc774 \ubd80\ub2f4\ud574\uc57c \ud588\ub2e4.<\/p>\n

\ud558\uc9c0\ub9cc \uc774\ubc88\uc5d0 \uc2dc\ud589\ub41c \uac1c\uc815\uc548\uc5d0\uc11c\ub294 \uc5f0\uad6c \ub300\uc0c1\uc744 \uc77c\ubcf8\ucc98\ub7fc \uc804\uc81c \ud658\uc790\ub85c \ub113\ud614\ub2e4. \ubbf8\uc6a9\uacfc \uc131\ud615 \ubaa9\uc801\ub9cc \uc544\ub2c8\ub77c\uba74 \uc0ac\uc6a9\ud560 \uc218 \uc788\ub294 \uc138\ud3ec\ub3c4 \uc704\ud5d8\ub3c4\uc5d0 \uad00\uacc4\uc5c6\uc774 \uc801\uc6a9\ud560 \uc218 \uc788\ub3c4\ub85d \ud588\ub2e4. \ub610 \uc2ec\uc758\ub97c \uac70\uccd0 \uce58\ub8cc \uc81c\ub3c4\ub97c \ud1b5\uacfc\ud558\uba74 \uc77c\uc815 \ube44\uc6a9\uc744 \ud658\uc790\uc5d0\uac8c \ubd80\uacfc\ud560 \uc218 \uc788\ub3c4\ub85d \uc870\uc815\ud588\ub2e4. \ub2e4\ub9cc \uc774 \uc81c\ub3c4\ub97c \ud1b5\ud55c \uc57d\ubb3c\uc758 \ud22c\uc57d \ud658\uc790 \ubc94\uc704\ub294 \uae30\uc874\ucc98\ub7fc \uc911\ub300\u00b7\ud76c\uadc0\u00b7\ub09c\uce58 \uc9c8\ud658\uc790\ub85c \uc81c\ud55c\uc744 \ub480\ub2e4.<\/p>\n

\uc7ac\uc0dd\uc758\ub8cc \ubd84\uc57c \ubc14\uc774\uc624\ucee8\uc124\ud305 \uae30\uc5c5\uc744 \uc6b4\uc601\ud588\ub358 \ud669\uc720\uacbd CTX \ub300\ud45c\ub294 “\uce58\ub8cc \uc81c\ub3c4\ub97c \ud1b5\ud574 \uc801\uc6a9\ub418\ub354\ub77c\ub3c4 \uc2e0\uc57d\uc73c\ub85c \uc0c1\uc5c5\ud654 \ud55c \uac83\uc740 \uc544\ub2c8\uae30 \ub54c\ubb38\uc5d0 \uc6d0\uac00\uc640 \uac1c\ubc1c\ube44 \ub4f1\uc744 \uc5b4\ub290 \uc815\ub3c4\uae4c\uc9c0 \ube44\uc6a9\uc73c\ub85c \uc0b0\uc815\ud574\uc57c \ud560\uc9c0 \ucd94\uac00 \ub17c\uc758\uac00 \ud544\uc694\ud558\ub2e4”\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\ud669 \ub300\ud45c\ub294 “\uc5f0\uad6c\uc790 \uc784\uc0c1\uc744 \ub9c8\uce5c \ub2e4\uc74c \uce58\ub8cc \uc81c\ub3c4\ub97c \ud0c0\uc9c4\ud558\ub294 \uac83\uc774\uae30 \ub54c\ubb38\uc5d0 \uccab \uc0ac\ub840\uac00 \ub098\uc624\ub824\uba74 \uc2dc\uac04\uc774 \uac78\ub9b4 \uac83”\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

\u25c7’\uc815\ucc45\uc704\u00b7\uc2ec\uc758\uc704’ \uc5ed\ud560\ub860 \ubd80\uac01, \uc548\uc804\uc131 \uad00\ub9ac\uac00 \uad00\uac74<\/strong><\/p>\n

\ucca8\uc0dd\ubc95 \uac1c\uc815\uc548\uc774 \uc2dc\ud589\ub428\uc5d0 \ub530\ub77c \uc7ac\uc0dd\uc758\ub8cc \uc5f0\uad6c \ubc94\uc704\ub098 \uce58\ub8cc \uc81c\ub3c4\uc758 \uc2ec\uc758\ub97c \ub2f4\ub2f9\ud558\uac8c \ub420 \ub450 \uc704\uc6d0\ud68c\uc758 \uc5ed\ud560\uc774 \ub354 \ucee4\uc9c8 \uc804\ub9dd\uc774\ub2e4.<\/p>\n

\uc774\ubc88 \ucca8\uc0dd\ubc95 \uac1c\uc815\uc548 \uc81c2\uc7a5 7\uc870\uc5d0 \ub530\ub77c \ud658\uc790 \ubc94\uc704\ub098 \uc704\ud5d8\ub3c4 \ubd84\ub958 \ub4f1\uc758 \uc0ac\ud56d\uc744 \uc2ec\uc758\ud558\uae30 \uc704\ud574 \ubcf4\uac74\ubcf5\uc9c0\ubd80 \uc18c\uc18d 21\uc778\uc73c\ub85c \uad6c\uc131\ub41c \uc815\ucc45\uc704\uc6d0\ud68c\ub97c \uc6b4\uc601\ud574\uc57c \ud55c\ub2e4. \ub610 \uc81c3\uc7a5 \uc81c 13\uc870\uc5d0 \ub530\ub77c \ubcf4\uac74\ubcf5\uc9c0\ubd80\uc640 \uc2dd\ud488\uc758\uc57d\ud488\uc548\uc804\ucc98 \ub4f1 \uacf5\ub3d9 \uc18c\uc18d\uc73c\ub85c \uc2ec\uc758\uc704\uc6d0\ud68c\ub97c \ub450\uc5b4\uc57c\ud558\uba70 \uc778\uc6d0\uc740 25\uc778\uc73c\ub85c \uc124\uc815\ub410\ub2e4. \uc2ec\uc758\uc704\uc6d0\ud68c\ub294 \uc5f0\uad6c\uc790 \uc784\uc0c1\uacc4\ud68d, \uce58\ub8cc \uacc4\ud68d \ub4f1\uc744 \uc2ec\uc758\ud55c\ub2e4.<\/p>\n

\ucca8\uc0dd\ubc95 \uac1c\uc815\uc548\uc5d0 \ub530\ub77c \uac1c\ubc1c \ubc0f \uce58\ub8cc \uc81c\ub3c4 \ub3c4\uc785 \uc0ac\ub840\uac00 \ub9ce\uc544\uc9c8 \uacbd\uc6b0 \uac00\uc7a5 \uc6b0\ub824\ub418\ub294 \ubd80\ubd84\uc740 \uc548\uc804\uc131\uc774\ub2e4. \uc0c1\uc5c5\ud654\ub97c \uac70\uce58\uba74 \uac80\uc99d\ub41c \uc18c\uc7ac\ub098 \uc7a5\ube44\uc744 \uac16\ucd98 GMP \uc2dc\uc124\uc5d0\uc11c \ubb3c\uc9c8\uc774 \uc0dd\uc0b0\ub41c\ub2e4. \ud558\uc9c0\ub9cc \uc5f0\uad6c\uc790 \uc784\uc0c1\uc744 \uac70\uccd0 \uce58\ub8cc \uc81c\ub3c4\ub97c \ud1b5\ud574 \ud604\uc7a5\uc5d0 \ub3c4\uc785\ub420 \uacbd\uc6b0 \uc774\ub7f0 \ubd80\ubd84\uc5d0\uc11c \uacf5\ubc31\uc774 \ubc1c\uc0dd\ud560 \uc218 \uc788\ub2e4.<\/p>\n

\uc774\ub97c \uad00\ub9ac\ud560 \uc815\ucc45\uc704\ub098 \uc2ec\uc758\uc704\uc758 \uc5ed\ud560\uc774 \uc911\uc694\ud574\uc9c8 \uc218\ubc16\uc5d0 \uc5c6\ub294 \uc774\uc720\ub2e4. \ubcf4\uac74\ubcf5\uc9c0\ubd80\ub294 \ub450 \uc704\uc6d0\ud68c\uc758 \uad6c\uc131 \uc778\uc6d0 \uc218\ub294 \ud5a5\ud6c4 \uac1c\ubc1c \uc218\uc694\uc5d0 \ub530\ub978 \uc5c5\ubb34\ub7c9 \ub4f1\uc744 \uadfc\uac70\ud574 \uc870\uc815\ub420 \uc5ec\uc9c0\uac00 \uc788\ub2e4\ub294 \uc785\uc7a5\uc744 \ub0b4\ub193\uace0 \uc788\ub2e4.<\/p>\n

\/ \uae40\uc9c4\ud638 \ub354\ubca8 \uae30\uc790<\/p>\n","protected":false},"excerpt":{"rendered":"

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